ISSN : 2146-3123
E-ISSN : 2146-3131

Sequential Evaluation of Pancreato-Biliary Findings in a Case with IgG4-Associated Cholangiopathy and Autoimmune Pancreatitis during Corticosteroid Treatment
İsmail Şerifoğlu 1, İbrahim İlker Öz 1, Yücel Üstündağ 2, Sevil Uygun İlikhan 3, Özlem Tokgöz 4
1Department of Radiology, Bülent Ecevit University School of Medicine, Zonguldak, Turkey
2Department of Gastroenterology, Bülent Ecevit University School of Medicine, Zonguldak, Turkey
3Department of Internal Medicine, Bülent Ecevit University School of Medicine, Zonguldak, Turkey
4Department of Radiology, Antalya Training and Research Hospital, Antalya, Turkey
DOI : 10.5152/balkanmedj.2016.15420

Abstract

Background: Immunoglobulin G4 (IgG4)-associated diseases mostly involve the pancreatico-biliary tree and pancreatic parenchyma. This disease complex is characterized by marked response to corticosteroid therapy and response to steroids is incorporated in the diagnostic algorithm of IgG4 associated diseases. However, there is much unknown about the sequences and duration of healing during the corticosteroid therapy in the literature.

Case Report: In this case report, we report a young male patient with IgG4 associated extrahepatic biliary stricture and autoimmune pancreatitis successfully treated with corticosteroids. Recovery in the laboratory and radiological radiological findings seemed to correlate well with the decrease in serum IgG4 levels in this patient. We also discussed sequences and the duration of healing in the pancreaticobiliary tree and pancreatic parenchymal manifestations in this case report.

Conclusion: There is a gap in our knowledge about the evaluation of response criteria after steroid trial with regard to the duration and sequences of healing in the pancreaticobiliary involvement in diagnosing IgG4-related biliary and pancreatic diseases.

Keywords : Autoimmune pancreatitis, corticosteroid, IgG4 associated diseases, IgG4, imaging

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