ISSN : 2146-3123
E-ISSN : 2146-3131

Translational Functional Neuroimaging in the Explanation of Depression
Drozdstoy Stoyanov1, Sevdalina Kandilarova1, Stefan Borgwardt3
1Department of Psychiatry and Medical Psychology Medical University Plovdiv, Plovdiv, Bulgaria
2Research Complex for Translational Neuroscience, Medical University Plovdiv, Plovdiv, Bulgaria
3Department of Psychiatry, University of Basel, Basel, Switzerland
DOI : 10.4274/balkanmedj.2017.1160

Summary

Translation as a notion and procedure is deeply embodied in medical science and education. It includes the possibility to translate data across disciplines in order to improve diagnosis and treatment procedures. The evidence accumulated by means of translation serves as vehicle for reification of medical diagnoses. There are established promising post hoc correlations between the different types of clinical tools (interviews and inventories) on one hand and neuroscience on the other. Insofar the different kinds of measures represent statistical correlations which still need to be integrated into diagnostic standards and procedures but this, as a whole, is a step forward towards a better understanding of the mechanisms underlying psychopathology in general and depression in particular. In the following lines, we will focus on functional magnetic resonance imaging studies using a trans-disciplinary approach and trying to establish the bridges between the different fields. We will selectively highlight research areas such as imaging genetics, imaging immunology and multimodal imaging related to depression, its diagnosis and management.
Keywords : Neuroscience, translational medical research, depression