ISSN : 2146-3123
E-ISSN : 2146-3131

Effects of Salmon Calcitonin on the Concentrations of Monoamines in Periaqueductal Gray in Formalin Test
Kaveh Rahimi1, Javad Sajedianfard1, Ali Akbar Owji2
1Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
2Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
DOI : 10.4274/balkanmedj.galenos.2019.2018.12.88
Pages : 263-269

Abstract

Background: The receptors of salmon calcitonin, located on certain areas of the brain such as the periaqueductal gray matter, are responsible for pain modulation.
Aims: The effects of intracerebroventricular injection of salmon calcitonin on the behavioral response to pain and on the levels of monoamines in the periaqueductal gray were explored using a biphasic animal model of pain.
Study Design: Animal exp