ISSN : 2146-3123
E-ISSN : 2146-3131

Alveolar Rhabdomyosarcoma in the Perianal Region in an Adult Patient
Fulya Öz Puyan 1, Latife Doğanay 2, A.Kemal Kutlu 2, Gülhan Aktaş 3, Şemsi Altaner 4
1Trakya Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Edirne
2Trakya Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı,Edirne
3Karaelmas Üniversitesi Tıp Fakültesi Histoloji Embriyoloji Anabilim Dalı, Zonguldak
4Trakya Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, Edirne
Pages : 157-161


The perianal region is an unusual localization for alveolar rhabdomyosarcoma in adults. A forty-fouryear- old woman presented with a fixed solid tumoral lesion about 4 cm in diameter in the entrance of the anal canal. Following an incisional biopsy, abdominoperineal resection was performed, during which a deep subcutaneous solid, nodular mass was detected below the anal canal, gray and white in color, and 6x5.5 cm in size. It did not have any relationship with the intestinal mucosa, but showed invasion to the subcutaneous fat tissue. Microscopic examination revealed a cellular tumor divided by marked fibrous septations and consisting of large oval-round pleomorphic cells with scanty eosinophilic cytoplasm in pseudoalveolar structures. Immunohistochemical and ultrastructural examinations yielded a diagnosis of alveolar rhabdomyosarcoma. The patient died a year after surgery because of multiple metastases.

Keywords : Anus neoplasms/surgery; diagnosis, differential; rhabdomyosarcoma / diagnosis /pathology/surgery
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