ISSN : 2146-3123
E-ISSN : 2146-3131

Follicular Growth Pattern Disease on Thyroid Fine-needle Aspiration Biopsy
Ebru Tastekin1, Şule Canberk2,3,4, Fernando C. Schmitt2,5,6
1Department of Pathology, Faculty of Medicine Trakya University, Edirne, Turkey
2Pathology Instituto de Investigação e Inovação em Saúde, University of Porto, Institute of Molecular Pathology and Immunology, Porto, Portugal
33Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Rua Júlio Amaral de Carvalho, Porto, Portugal
4Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Rua Jorge de Viterbo Ferreira, Porto, Portugal
5Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Alameda Professor Hernâni Monteiro, Porto, Portugal
6CINTESIS@RISE, Alameda Professor Hernâni Monteiro, Porto, Portugal
DOI : 10.4274/balkanmedj.galenos.2022.2022-5-17
Pages : 230-238

Thyroid nodules are a common worldwide health problem and a diagnostic challenge for clinicians and cytopathologists. Follicular growth pattern constitutes the majority of thyroid lesions. Thyroid nodules can be neoplastic or non-neoplastic, and neoplastic nodules can be classified as benign, malignant, or gray zone. Gray zone lesions include different benign and malignant entities that might be resulted in unnecessary thyroidectomies with risk of morbidity and higher health care costs. Depending on the cellularity, most cases might fall into the follicular neoplasia (FN)/ suspicious for FN (SFN) category or follicular lesion of undetermined significance (FLUS) in The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). Pathologists must be aware of the relationship between this diagnostic category and follow-up patient management and avoid over-diagnosing by mastering the diagnostic criteria.

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