ISSN : 2146-3123
E-ISSN : 2146-3131

Microfilariae Prevalence and its Association with Anemia Among First-time Blood Donors in Lambaréné, Gabon
Soulemane Parkouda1, Mahmoudou Saidou2, Cyrille Bisseye3
1Biomedical Laboratory, Centre Hospitalier Régional Georges Rawiri, Lambaréné, Gabon
2Biostatistiques, Centre de Recherches Medicales de Lambaréné, Lambaréné, Gabon
3Biologie/Unité de Recherche en Sciences Biologiques, Université des Sciences et Techniques de Masuku, Franceville, Gabon
DOI : 10.4274/balkanmedj.galenos.2023.2023-9-86

Background: Anemia remains a significant public health concernin Gabon, particularly among children, adolescents, and females.Gabon is also home to two major species of filarial worms, Loa andMansonella spp., which cause microfilaremia. The epidemiologicalnexus between hemoglobin (Hb) concentrations and microfilaremia inGabonese first-time blood donors remains unknown.
Aims: This study aimed to understand better the epidemiologicalrelationship between anemia and microfilaremia to improve donorselection and management protocols.
Study Design: This retrospective and analytical study was conductedamong first-time blood donors in Lambaréné between March 2018 andOctober 2019.
Methods: Participants aged 16-65 years old and weighing a minimumof 50 kg were enrolled using standard donor selection criteria.An automatic hematological analyzer was used to quantify Hbconcentrations, and microscopy techniques were used to detect thepresence of microfilariae.
Results: Microfilariae were found in 4.8% (35/723) of the 723 firsttimeblood donors from Lambaréné. Anemia was classified as mildin 35.5% (257/723) and moderate in 1% (7/723). No significantassociations were found between the distribution of microfilariae andvariables such as age, sex, socioprofessional classification, maritalstatus, or residence. Blood group O donors had a higher prevalence ofmicrofilariae (6%) than non-O donors (2.7%). However, the observeddifference was not statistically significant (AOR =2.3, p = 0.052).Furthermore, microfilariae were associated with increased moderateanemia (3.7% vs. 29%, AOR =15.6, p = 0.003).
Conclusion: Our findings highlight microfilaremia as a possibleetiological cause of anemia among Gabonese blood donors,emphasizing the need for further research and a potential review ofdonor management strategies.

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