ISSN : 2146-3123
E-ISSN : 2146-3131

Mediterranean Spotted Fever: Retrospective Evaluation of 16 Cases
Emel Yılmaz 1, Halis Akalın 1, Yasemin Heper 1, Ebru Kılıçaslan 1, Aslıhan Öztüfekçi 1, Emine Sevgican 1, Safiye Helvacı 1, Okan Töre 1, Aynur Engin 2
1Department of Infectious Diseases and Microbiology, Medical Faculty of Uludağ University, Bursa
2Department of Infectious Diseases and Microbiology, Medical Faculty of Cumhuriyet University, Sivas
DOI : 10.5174/tutfd.2009.01368.1
Pages : 167-171


Objectives: Mediterranean spotted fever (MSF) is an acute febrile, zoonotic disease caused by Rickettsia conorii and endemic infectious disease in Mediterranean countries.

Patients and Methods: In this study, a retrospective examination of 16 cases (4 females, 12 males; mean age 38.9±13.0; range 18 to 64 years) that were diagnosed with rickettsioses between 1987-2007 was performed. Diagnosis of MSF was based upon epidemiological and clinical features, indirect immunofluorescence antibody (IFA), as well as response to doxycycline therapy.

Results: High fever and maculopapular rash were present in all cases. Palmar and plantar rash were evident in 13 (81.3%) and eschar in eight (50%) cases. All cases responded to treatment within 2±0.9 days, and no death was observed.

Conclusion: Mediterranean spotted fever should be considered in the differential diagnosis of all patients admitting with fever, maculopapular rash, headache and/or musclejoint pain during spring, summer and autumn.

Keywords : Mediterranean spotted fever; Maculopapular rash; fever
Viewed : 2449
Downloaded : 1404