ISSN : 2146-3123
E-ISSN : 2146-3131

Meta-analysis of 21 randomized control studies: There is no evidence that vitamin D protects against heart disease

In this meta-analysis of randomized clinical trials published published online June 19, 2019 in JAMA cardiology that included more than 83 000 participants, vitamin D supplementation was not associated with reduced risks of major adverse cardiovascular events, myocardial infarction, stroke, cardiovascular disease mortality, or all-cause mortality compared with placebo. These results suggest that vitamin D supplementation may not confer cardiovascular protection and may not be indicated for this purpose.