ISSN : 2146-3123
E-ISSN : 2146-3131

Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium
Dilek Memiş 1, MÜŞERREF OTKUN 2, MERAL BAHAR 1, Necdet Süt 3
1Departments of Anesthesiology, Medical Faculty of Trakya University, Edirne
2Department of Microbiology, Medical Faculty of 19 Mart University, Çanakkale
3Departments of Biostatistics, Medical Faculty of Trakya University, Edirne
Pages : 100-104

Abstract

Objectives: We studied in vivo growth of Escherichia coli in atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, and vecuronium.

Patients and Methods: The pathogen was exposed to atracurium, rocuronium, mivacurium, cisatracurium, pancuronium and vecuronium for 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and 24 h at room temperature, respectively.

Results: The mean colony counts of Escherichia coli after exposure to rocuronium was significantly lower than the counts after exposure to atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p=0.002, 0.000, 0.000, 0.001, and 0.002, respectively). No significant difference was found with respect to the mean colony counts with atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p<0.05).

Conclusion: Rocuronium had more powerful antimicrobial effects than the other neuromuscular agents.

Turkish

Amaç: Biz çalışmamızda atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumun Escherichia coli üremesi üzerine olan etkinliğini araştırdık.

Hastalar ve Yöntemler: Patojen bakteri, atrakuryum, rokuronyum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyum ile 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, ve 24 saat oda sıcaklığında temas ettirildi.

Bulgular: Escherichia coli ortalama koloni sayısı rokuronyumda istatiksel anlamlı olarak atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumdan daha düşük saptandı (sırasıyla p=0.002, 0.000, 0.000, 0.001, ve 0.002). Atrakuryum, mivakuryum, sisatrakuryum, pankuronyum ve vekuronyumda ortalama koloni sayısı açısından anlamlı fark saptanmadı (p<0.05).

Sonuç: Rokuronyum, diğer nöromusküler kas gevşetici ajanlardan daha kuvvetli antimikrobiyal etki gösterdi.

Keywords : Atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, vecuronium, bacterial contamination, Escherichia coli

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