ISSN : 2146-3123
E-ISSN : 2146-3131

Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl
Vehbi Doğan 1, Erhan Karaaslan 2, Samet Özer 2, Rüveyda Gümüşer 2, Resul Yılmaz 2
1Department of Pediatric Cardiology, Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey
2Department of Pediatrics, Gaziosmanpaşa University School of Medicine, Tokat, Turkey
DOI : 10.5152/balkanmedj.2016.150371
Pages : 470-472

Abstract

Background: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic  lymphohistiocytosis can complicate the course of Kawasaki disease. Rare cases of secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of Kawasaki disease have been reported.

Case Report: We report here a 4 month-old girl with diffuse coronary ectasia and secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of incomplete Kawasaki disease.

Conclusion: Due to the large overlap in clinical symptoms, the presence of atypical findings for Kawasaki disease should suggest the possible diagnosis of hemophagocytic lymphohistiocytosis in these patients.

Keywords : Coronary artery dilatation, hemophagocytic lymphohistiocytosis, Kawasaki disease, macrophage activation syndrome
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