ISSN : 2146-3123
E-ISSN : 2146-3131

Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus
Sahra Kırmusaoğlu 1, Seyhun Yurdugül 1, Esra Koçoğlu 2
1Department of Biology, Faculty of Sciences, Abant İzzet Baysal University, Bolu, Turkey
2Department of Microbiology, İzzet Baysal Faculty of Medicine Research and Education Hospital, Abant İzzet Baysal University, Bolu, Turkey
DOI : 10.5152/balkanmedj.2011.023
Pages : 84-87

Abstract

Objective: Staphylococcus aureus (S. aureus) is one of the most commonly isolated bacterial pathogens in hospitals, and the most frequent cause of nosocomial infections. Nosocomial staphylococcal foreign-body infections related to biofilm formation are a serious threat, demanding new therapeutic and preventive strategies. Implantation of intravenous catheters and surgical implantation of prosthetic implants carry a risk of infection. In order to prevent all these effects of biofilms, a study was designed to observe the possible antibacterial effect of sumach (Rhus coriaria) on the biofilm formation of S. aureus.

Material and Methods: The influence of varying concentrations of sumach on the formation of biofilms by 13 strains of Staphylococcus aureus was tested by a microelisa assay.

Results: The significant differences between varying concentrations of sumach (0.1, 0.2, 0.5 and 1.0 μl/ml) were observed in four methicillin resistant Staphylococcus aureus (MRSA) and nine methicillin sensitive Staphylococcus aureus (MSSA) (p<0.05). In bacteria, a dose-related decrease in the formation of slime, which is a major virulence factor of staphylococcal infections, was observed.

Conclusion: In our study, using 0.1, 0.2, 0.5 and 1.0 μl/ml of sumach, thirteen strains lost, 17%, 22%, 28% and 48% respectively of their capacity to produce biofilms. Sumach, which is a herbal product, can decrease the formation of biofilm, which is a major virulence factor in staphylococcal infections.

Keywords : Staphylococcus aureus, biofilm formation, Rhus coriaria, Indwelling device-associated infections
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