ISSN : 2146-3123
E-ISSN : 2146-3131

The Value of Ensari’s Proposal in Evaluating the Mucosal Pathology of Childhood Celiac Disease: Old Classification versus New Version
Servet Güreşci 1, Gülçin Güler Şimşek 1, Şamil Hızlı 2
1Department of Pathology, Keçiören Training and Research Hospital, Ankara, Turkey
2Department of Pediatric Gastroenterology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
DOI : 10.5152/balkanmedj.2012.016
Pages : 281-284


Objective: Small intestinal biopsy remains the gold standard in diagnosing celiac disease (CD); however, the wide spectrum of histopathological states and differential diagnosis of CD is still a diagnostic problem for pathologists. Recently, Ensari reviewed the literature and proposed an update of the histopathological diagnosis and classification for CD.

Materials and Methods: In this study, the histopathological materials of 54 children in whom CD was diagnosed at our hospital were reviewed to compare the previous Marsh and Modified Marsh-Oberhuber classifications with this new proposal. 

Results: In this study, we show that the Ensari classification is as accurate as the Marsh and Modified Marsh classifications in describing the consecutive states of mucosal damage seen in CD.

Conclusions: Ensari’s classification is simple, practical and facilitative in diagnosing and subtyping of mucosal pathology of CD

Keywords : Celiac disease, marsh classification, modified Marsh-Oberhuber classification, Ensari classification
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