ISSN : 2146-3123
E-ISSN : 2146-3131

Human Bocavirus (HBoV) DNA’sının Multipleks PCR Analizi ile Saptanması: Postmortem Olgu Sunumu
Nihan Ziyade 1, Neval Elgörmüş 1, Gözde Şirin 2, Taner Daş 3
1Postmortem Microbiology Laboratory, Council of Forensic Medicine, İstanbul, Turkey
2Autopsy Unit, Mortuary Office, Council of Forensic Medicine, İstanbul, Turkey
3Histopathology Unit, Mortuary Office, Council of Forensic Medicine, İstanbul, Turkey
DOI : 10.5152/balkanmedj.2015.15254
Pages : 226-229


Background: Human bocavirus (HBoV) is a virus belonging to the Parvoviridae family, which has been newly discovered to be associated with respiratory tract infections in children. There are many reports worldwide on the endemicity of this virus. Since it is relatively new, it is not routinely detected in clinical laboratory investigations.

Case Report: We demonstrated that HBoV infection caused the death of a 5-month-old girl with a history of high fever and wheezing. Human bocavirus (HBoV 1/2/3/4) was found in a nasopharyngeal swab, paraffin-embedded lung tissue and stool samples by multiplex PCR methods using postmortem microbiological analysis.

Conclusion: This case suggests that lower respiratory tract infections due to HBoV may cause severe and life-threatening diseases. Postmortem microbiology is useful in both clinical and forensic autopsies, and allows a suspected infection to be confirmed. To our knowledge, this report is the first document of a HBoV postmortem case in Turkey.

Keywords : Adli bilimler, Human Bocavirus, multipleks PCR, otopsi, postmortem mikrobiyoloji, solunum yolu enfeksiyonu

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